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nucleoSim: Generate synthetic nucleosome maps ===================== [![R-CMD-check-bioc](]( [![codecov](]( [![License: Artistic-2.0](]( This *nucleoSim* package generate synthetic nucleosome maps using parameters given by users. Three different distributions are available: Normal, Student and Uniform. The package has been largely inspired by the *Generating synthetic maps* section of the Bioconductor [nucleR]( package (Flores and Orozco, 2011). ## Bioconductor Package ## [![Bioconductor Time](]( "Bioconductor status") *nucleoSim* is now an official package of [Bioconductor]( The current release can be directly downloaded from their website: [Current release]( ## Citing ## If you use this package for a publication, we would ask you to cite the following: > Samb R, Khadraoui K, Belleau P, et al. (2015). "Using informative Multinomial-Dirichlet prior in a t-mixture with reversible jump estimation of nucleosome positions for genome-wide profiling." Statistical Applications in Genetics and Molecular Biology. Volume 14, Issue 6, Pages 517-532, ISSN (Online) 1544-6115, ISSN (Print) 2194-6302, December 2015, <a href="">doi: 10.1515/sagmb-2014-0098</a> > Flores O and Orozco M (2011). “nucleR: a package for non-parametric nucleosome positioning.” Bioinformatics, 27, pp. 2149–2150. <a href="">doi: 10.1093/bioinformatics/btr345</a> ## Authors ## [Rawane Samb]( "Rawane Samb"), [Astrid Desch&ecirc;nes]( "Astrid Desch&ecirc;nes"), [Pascal Belleau]( "Pascal Belleau") and [Arnaud Droit]( "Arnaud Droit"). ## Maintainer ## [Astrid Desch&ecirc;nes]( "Astrid Desch&ecirc;nes") ## License ## This package and the underlying *nucleoSim* code are distributed under the Artistic license 2.0. You are free to use and redistribute this software. For more information on Artistic 2.0 License see []( ## Bugs/Feature requests ## If you have any bugs or feature requests, [let us know]( Thanks!