nucleoSim: Generate synthetic nucleosome maps ===================== [](https://github.com/adeschen/nucleoSim/actions/workflows/check-bioc.yaml) [](https://codecov.io/gh/ArnaudDroitLab/nucleoSim) [](https://opensource.org/licenses/Artistic-2.0) This *nucleoSim* package generate synthetic nucleosome maps using parameters given by users. Three different distributions are available: Normal, Student and Uniform. The package has been largely inspired by the *Generating synthetic maps* section of the Bioconductor [nucleR](http://www.bioconductor.org/packages/release/bioc/html/nucleR.html) package (Flores and Orozco, 2011). ## Bioconductor Package ## [](http://bioconductor.org/packages/nucleoSim "Bioconductor status") *nucleoSim* is now an official package of [Bioconductor](http://bioconductor.org/). The current release can be directly downloaded from their website: [Current release](http://bioconductor.org/packages/nucleoSim) ## Citing ## If you use this package for a publication, we would ask you to cite the following: > Samb R, Khadraoui K, Belleau P, et al. (2015). "Using informative Multinomial-Dirichlet prior in a t-mixture with reversible jump estimation of nucleosome positions for genome-wide profiling." Statistical Applications in Genetics and Molecular Biology. Volume 14, Issue 6, Pages 517-532, ISSN (Online) 1544-6115, ISSN (Print) 2194-6302, December 2015, <a href="http://dx.doi.org/10.1515/sagmb-2014-0098">doi: 10.1515/sagmb-2014-0098</a> > Flores O and Orozco M (2011). “nucleR: a package for non-parametric nucleosome positioning.” Bioinformatics, 27, pp. 2149–2150. <a href="http://dx.doi.org/10.1093/bioinformatics/btr345">doi: 10.1093/bioinformatics/btr345</a> ## Authors ## [Rawane Samb](https://ca.linkedin.com/in/rawanesamb "Rawane Samb"), [Astrid Desch&ecirc;nes](http://ca.linkedin.com/in/astriddeschenes "Astrid Desch&ecirc;nes"), [Pascal Belleau](http://ca.linkedin.com/in/pascalbelleau "Pascal Belleau") and [Arnaud Droit](http://ca.linkedin.com/in/drarnaud "Arnaud Droit"). ## Maintainer ## [Astrid Desch&ecirc;nes](http://ca.linkedin.com/in/astriddeschenes "Astrid Desch&ecirc;nes") ## License ## This package and the underlying *nucleoSim* code are distributed under the Artistic license 2.0. You are free to use and redistribute this software. For more information on Artistic 2.0 License see [http://opensource.org/licenses/Artistic-2.0](http://opensource.org/licenses/Artistic-2.0) ## Bugs/Feature requests ## If you have any bugs or feature requests, [let us know](https://github.com/arnauddroitlab/nucleoSim/issues). Thanks!