# spillR Find the paper here: https://academic.oup.com/bioinformatics/article/40/6/btae337/7689679. ## Description Channel interference in mass cytometry can cause spillover and may result in miscounting of protein markers. We develop a nonparametric finite mixture model, and use the mixture components to estimate the probability of spillover. We implement our method using expectation-maximization to fit the mixture model. ## Installation Our R package is available on [Bioconductor](https://bioconductor.org/packages/spillR): ``` r if (!require("BiocManager", quietly = TRUE)) install.packages("BiocManager") # The following initializes usage of Bioc devel BiocManager::install(version='devel') BiocManager::install("spillR") ```