Package: scHOT Type: Package Title: single-cell higher order testing Version: 1.15.0 Authors@R: c( person("Shila", "Ghazanfar", email = "shazanfar@gmail.com", role = c("aut", "cre") ), person("Yingxin", "Lin", email = "yingxin.lin@sydney.edu.au", role = c("aut") )) Description: Single cell Higher Order Testing (scHOT) is an R package that facilitates testing changes in higher order structure of gene expression along either a developmental trajectory or across space. scHOT is general and modular in nature, can be run in multiple data contexts such as along a continuous trajectory, between discrete groups, and over spatial orientations; as well as accommodate any higher order measurement such as variability or correlation. scHOT meaningfully adds to first order effect testing, such as differential expression, and provides a framework for interrogating higher order interactions from single cell data. License: GPL-3 Encoding: UTF-8 LazyData: true Depends: R (>= 4.0) Imports: S4Vectors (>= 0.24.3), SingleCellExperiment, Matrix, SummarizedExperiment, IRanges, methods, stats, BiocParallel, reshape, ggplot2, igraph, grDevices, ggforce, graphics RoxygenNote: 7.1.0 Suggests: knitr, markdown, rmarkdown, scater, scattermore, scales, matrixStats, deldir VignetteBuilder: knitr biocViews: GeneExpression, RNASeq, Sequencing, SingleCell, Software, Transcriptomics