# Introduction
This package utilizes data derived from the
[MEROPS database](https://www.ebi.ac.uk/merops/) and facilitates retrieving
proteolytic enzymes data by mapping peptide termini to known sites where a
protease cleaves.
# Installation
## Using devtools
```r
install.packages("devtools")
library("devtools")
install_github("martinry/proteasy")
```
## Using Bioconductor
```r
if (!requireNamespace("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("proteasy")
```
# Usage
```r
# Example 1
searchSubstrate(protein = "P01042", summarize = TRUE)
# Example 2
searchProtease(protein = "P39900", summarize = TRUE)
# Example 3
protein <- c("P02671", "P02671", "P68871", "P01011")
peptide <- c("FEEVSGNVSPGTR", "FVSETESR", "LLVVYPW", "ITLLSAL")
res <- findProtease(protein = protein, peptide = peptide,
organism = "Homo sapiens")
substrates(res)
proteases(res)
cleavages(res)
# Example 4
browseProtease("P07339", keytype = "UniprotID") # (opens web browser)
```
