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README.md
# powerTCR: modeling the clone size distribution of the TCR repertoire This is an R package for fitting the discrete gamma-GPD spliced threshold model to a distribution of clone sizes. The package contains tools needed to perform all of the analyses found in __our paper (pending)__. ## Installation Install and load this package from BioConductor by typing in R: ```{r} if (!requireNamespace("BiocManager", quietly=TRUE)) install.packages("BiocManager") BiocManager::install("powerTCR") ``` or take it directly from from GitHub with: ```{r} library(devtools) install_github("hillarykoch/powerTCR") library(powerTCR) ``` ## Getting going See the [package vignette](/vignettes/powerTCR.Rmd) for a detailed walkthrough of package features. ## Citation Paper yet to appear. See our [preprint on bioRvix:](https://www.biorxiv.org/content/early/2018/04/07/297119) Hillary Koch, Dmytro Starenki, Sara J Cooper, Richard M Myers, Qunhua Li bioRxiv 297119; doi: https://doi.org/10.1101/297119