[](https://travis-ci.org/belleau/methInheritSim) [](https://codecov.io/gh/belleau/methInheritSim) [](https://opensource.org/licenses/Artistic-2.0) # Whole-Genome Inherited Bisulphite Sequencing Data Simulation # The **methInheritSim** package generates simulated multigenerational DMS datasets that are useful to evaluate the power and the false discovery rate of experiment design analysis, such as the methylInheritance [methylInheritance](http://bioconductor.org/packages/methylInheritance) package does. The multigenerational DMS datasets can also be used to compare the efficiency of different inheritance detection software. ## Citing ## If you use this package for a publication, we would ask you to cite the following: > Pascal Belleau, Astrid Deschênes, Marie-Pier Scott-Boyer, Romain Lambrot, Mathieu Dalvai, Sarah Kimmins, Janice Bailey, Arnaud Droit; Inferring and modeling inheritance of differentially methylated changes across multiple generations, Nucleic Acids Research, Volume 46, Issue 14, 21 August 2018, Pages e85. DOI: https://doi.org/10.1093/nar/gky362 ## Bioconductor Package ## [](http://bioconductor.org/packages/release/bioc/html/methInheritSim.html "Bioconductor status") **methInheritSim** is now an official package of [Bioconductor](http://bioconductor.org/). The current release can be directly downloaded from their website: [Current release](http://bioconductor.org/packages/methInheritSim) ## Description of Package Functionality ## The vignette of the **methInheritSim** package, which is a document that provides a task-oriented description of the package functionality, is available on Bioconductor website: [methInheritSim vignette](http://bioconductor.org/packages/release/bioc/vignettes/methInheritSim/inst/doc/methInheritSim.html) ## Authors ## [Pascal Belleau](http://ca.linkedin.com/in/pascalbelleau "Pascal Belleau"), [Astrid Deschênes](http://ca.linkedin.com/in/astriddeschenes "Astrid Deschênes") and [Arnaud Droit](http://ca.linkedin.com/in/drarnaud "Arnaud Droit"). See [Arnaud Droit Lab](http://bioinformatique.ulaval.ca "Arnaud Droit Lab") website. ## Maintainer ## [Pascal Belleau](http://ca.linkedin.com/in/pascalbelleau "Pascal Belleau") ## License ## This package and the underlying **methInheritSim** code are distributed under the Artistic license 2.0. You are free to use and redistribute this software. For more information on Artistic 2.0 License see [http://opensource.org/licenses/Artistic-2.0](http://opensource.org/licenses/Artistic-2.0) ## Bugs/Feature requests ## If you have any bugs or feature requests, [let us know](https://github.com/belleau/methInheritSim/issues). Thanks!