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[![Build Status](]( [![codecov](]( [![License: Artistic-2.0](]( # Whole-Genome Inherited Bisulphite Sequencing Data Simulation # The **methInheritSim** package generates simulated multigenerational DMS datasets that are useful to evaluate the power and the false discovery rate of experiment design analysis, such as the methylInheritance [methylInheritance]( package does. The multigenerational DMS datasets can also be used to compare the efficiency of different inheritance detection software. ## Citing ## If you use this package for a publication, we would ask you to cite the following: > Pascal Belleau, Astrid DeschĂȘnes, Marie-Pier Scott-Boyer, Romain Lambrot, Mathieu Dalvai, Sarah Kimmins, Janice Bailey, Arnaud Droit; Inferring and modeling inheritance of differentially methylated changes across multiple generations, Nucleic Acids Research, Volume 46, Issue 14, 21 August 2018, Pages e85. DOI: ## Bioconductor Package ## [![Bioconductor Time](]( "Bioconductor status") **methInheritSim** is now an official package of [Bioconductor]( The current release can be directly downloaded from their website: [Current release]( ## Description of Package Functionality ## The vignette of the **methInheritSim** package, which is a document that provides a task-oriented description of the package functionality, is available on Bioconductor website: [methInheritSim vignette]( ## Authors ## [Pascal Belleau]( "Pascal Belleau"), [Astrid Deschênes]( "Astrid Deschênes") and [Arnaud Droit]( "Arnaud Droit"). See [Arnaud Droit Lab]( "Arnaud Droit Lab") website. ## Maintainer ## [Pascal Belleau]( "Pascal Belleau") ## License ## This package and the underlying **methInheritSim** code are distributed under the Artistic license 2.0. You are free to use and redistribute this software. For more information on Artistic 2.0 License see []( ## Bugs/Feature requests ## If you have any bugs or feature requests, [let us know]( Thanks!