... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.14.0 |
|
3 |
+Version: 1.15.0 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.13.0 |
|
3 |
+Version: 1.14.0 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.12.0 |
|
3 |
+Version: 1.13.0 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.11.1 |
|
3 |
+Version: 1.12.0 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.11.0 |
|
3 |
+Version: 1.11.1 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.10.0 |
|
3 |
+Version: 1.11.0 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.9.0 |
|
3 |
+Version: 1.10.0 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.8.0 |
|
3 |
+Version: 1.9.0 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.7.1 |
|
3 |
+Version: 1.8.0 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.8.0 |
|
3 |
+Version: 1.7.1 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.7.2 |
|
3 |
+Version: 1.8.0 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.5.5 |
|
3 |
+Version: 1.7.2 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.5.4 |
|
3 |
+Version: 1.5.5 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.5.3 |
|
3 |
+Version: 1.5.4 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.5.2 |
|
3 |
+Version: 1.5.3 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.5.1 |
|
3 |
+Version: 1.5.2 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.5.0 |
|
3 |
+Version: 1.5.1 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.4.0 |
|
3 |
+Version: 1.5.0 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.3.0 |
|
3 |
+Version: 1.4.0 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.2.0 |
|
3 |
+Version: 1.3.0 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.1.0 |
|
3 |
+Version: 1.2.0 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 1.0.0 |
|
3 |
+Version: 1.1.0 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
1 | 1 |
old mode 100755 |
2 | 2 |
new mode 100644 |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 0.99.9 |
|
3 |
+Version: 1.0.0 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 0.99.8 |
|
3 |
+Version: 0.99.9 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 0.99.7 |
|
3 |
+Version: 0.99.8 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 0.99.6 |
|
3 |
+Version: 0.99.7 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -19,7 +19,7 @@ Description: epihet is an R-package that calculates the epigenetic |
19 | 19 |
created by calculating the differential heterogeneity of the samples. |
20 | 20 |
And we construct co-epihet network and perform network analysis. |
21 | 21 |
Depends: |
22 |
- R(>= 3.4.1), |
|
22 |
+ R(>= 3.6), |
|
23 | 23 |
GenomicRanges, |
24 | 24 |
IRanges, |
25 | 25 |
S4Vectors, |
... | ... |
@@ -19,7 +19,7 @@ Description: epihet is an R-package that calculates the epigenetic |
19 | 19 |
created by calculating the differential heterogeneity of the samples. |
20 | 20 |
And we construct co-epihet network and perform network analysis. |
21 | 21 |
Depends: |
22 |
- R(>= 3.6), |
|
22 |
+ R(>= 3.4.1), |
|
23 | 23 |
GenomicRanges, |
24 | 24 |
IRanges, |
25 | 25 |
S4Vectors, |
... | ... |
@@ -43,7 +43,7 @@ Imports: |
43 | 43 |
WGCNA, |
44 | 44 |
ReactomePA |
45 | 45 |
Encoding: UTF-8 |
46 |
-RoxygenNote: 6.0.1 |
|
46 |
+RoxygenNote: 6.1.1 |
|
47 | 47 |
Suggests: |
48 | 48 |
knitr, |
49 | 49 |
clusterProfiler, |
... | ... |
@@ -1,6 +1,6 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 0.99.5 |
|
3 |
+Version: 0.99.6 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
... | ... |
@@ -19,7 +19,7 @@ Description: epihet is an R-package that calculates the epigenetic |
19 | 19 |
created by calculating the differential heterogeneity of the samples. |
20 | 20 |
And we construct co-epihet network and perform network analysis. |
21 | 21 |
Depends: |
22 |
- R(>= 3.5.1), |
|
22 |
+ R(>= 3.6), |
|
23 | 23 |
GenomicRanges, |
24 | 24 |
IRanges, |
25 | 25 |
S4Vectors, |
... | ... |
@@ -1,10 +1,11 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Version: 0.99.4 |
|
3 |
+Version: 0.99.5 |
|
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
5 | 5 |
email = "Xiaowen.Chen@jax.org"), |
6 | 6 |
person("Haitham", "Ashoor",role = "aut"), |
7 | 7 |
person("Ryan", "Musich", role = "aut"), |
8 |
+ person("Mingsheng","Zhang",role="aut"), |
|
8 | 9 |
person("Jiahui","Wang",role = "aut"), |
9 | 10 |
person("Sheng", "Li", role = "aut")) |
10 | 11 |
Description: epihet is an R-package that calculates the epigenetic |
... | ... |
@@ -18,7 +19,7 @@ Description: epihet is an R-package that calculates the epigenetic |
18 | 19 |
created by calculating the differential heterogeneity of the samples. |
19 | 20 |
And we construct co-epihet network and perform network analysis. |
20 | 21 |
Depends: |
21 |
- R(>= 3.4.1), |
|
22 |
+ R(>= 3.5.1), |
|
22 | 23 |
GenomicRanges, |
23 | 24 |
IRanges, |
24 | 25 |
S4Vectors, |
... | ... |
@@ -1,4 +1,4 @@ |
1 |
-Package: EpiHet |
|
1 |
+Package: epihet |
|
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 | 3 |
Version: 0.99.4 |
4 | 4 |
Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
... | ... |
@@ -7,13 +7,13 @@ Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
7 | 7 |
person("Ryan", "Musich", role = "aut"), |
8 | 8 |
person("Jiahui","Wang",role = "aut"), |
9 | 9 |
person("Sheng", "Li", role = "aut")) |
10 |
-Description: EpiHet is an R-package that calculates the epigenetic |
|
10 |
+Description: epihet is an R-package that calculates the epigenetic |
|
11 | 11 |
heterogeneity between cancer cells and/or normal cells. The functions |
12 | 12 |
establish a pipeline that take in bisulfite sequencing data from multiple |
13 | 13 |
samples and use the data to track similarities and differences in |
14 | 14 |
epipolymorphism,proportion of discordantly methylated sequencing reads |
15 | 15 |
(PDR),and Shannon entropy values at epialleles that are shared between |
16 |
- the samples.EpiHet can be used to perform analysis on the data by creating |
|
16 |
+ the samples.epihet can be used to perform analysis on the data by creating |
|
17 | 17 |
pheatmaps, box plots, PCA plots, and t-SNE plots. MA plots can also be |
18 | 18 |
created by calculating the differential heterogeneity of the samples. |
19 | 19 |
And we construct co-epihet network and perform network analysis. |
... | ... |
@@ -42,7 +42,7 @@ Imports: |
42 | 42 |
WGCNA, |
43 | 43 |
ReactomePA |
44 | 44 |
Encoding: UTF-8 |
45 |
-RoxygenNote: 6.1.1 |
|
45 |
+RoxygenNote: 6.0.1 |
|
46 | 46 |
Suggests: |
47 | 47 |
knitr, |
48 | 48 |
clusterProfiler, |
... | ... |
@@ -1,38 +1,55 @@ |
1 |
-Package: epihet |
|
1 |
+Package: EpiHet |
|
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 |
-Date: 2018-04-10 |
|
4 |
-Version: 0.99.3 |
|
5 |
-Authors@R: c(person("Xiaowen", "Chen", email = "Xiaowen.Chen@jax.org", |
|
6 |
- role = c("aut", "cre")),person("Haitham", "Ashoor", |
|
7 |
- role = c("aut")),person("Ryan", "Musich", role = c("aut")), |
|
8 |
- person("Jiahui","Wang",role = "aut"),person("Sheng", "Li", role = "aut")) |
|
9 |
-Description: epihet is an R-package that calculates the epigenetic |
|
3 |
+Version: 0.99.4 |
|
4 |
+Authors@R: c(person("Xiaowen", "Chen", role = c("aut", "cre"), |
|
5 |
+ email = "Xiaowen.Chen@jax.org"), |
|
6 |
+ person("Haitham", "Ashoor",role = "aut"), |
|
7 |
+ person("Ryan", "Musich", role = "aut"), |
|
8 |
+ person("Jiahui","Wang",role = "aut"), |
|
9 |
+ person("Sheng", "Li", role = "aut")) |
|
10 |
+Description: EpiHet is an R-package that calculates the epigenetic |
|
10 | 11 |
heterogeneity between cancer cells and/or normal cells. The functions |
11 | 12 |
establish a pipeline that take in bisulfite sequencing data from multiple |
12 | 13 |
samples and use the data to track similarities and differences in |
13 | 14 |
epipolymorphism,proportion of discordantly methylated sequencing reads |
14 | 15 |
(PDR),and Shannon entropy values at epialleles that are shared between |
15 |
- the samples.epihet can be used to perform analysis on the data by creating |
|
16 |
+ the samples.EpiHet can be used to perform analysis on the data by creating |
|
16 | 17 |
pheatmaps, box plots, PCA plots, and t-SNE plots. MA plots can also be |
17 | 18 |
created by calculating the differential heterogeneity of the samples. |
18 | 19 |
And we construct co-epihet network and perform network analysis. |
19 | 20 |
Depends: |
20 |
- R(>= 3.5),GenomicRanges, IRanges, S4Vectors,ggplot2,foreach,Rtsne, |
|
21 |
+ R(>= 3.4.1), |
|
22 |
+ GenomicRanges, |
|
23 |
+ IRanges, |
|
24 |
+ S4Vectors, |
|
25 |
+ ggplot2, |
|
26 |
+ foreach, |
|
27 |
+ Rtsne, |
|
21 | 28 |
igraph |
22 | 29 |
License: Artistic-2.0 |
23 | 30 |
biocViews: |
24 | 31 |
DNAMethylation, Epigenetics, MethylSeq, Sequencing, Software |
25 | 32 |
Imports: |
26 |
- data.table, doParallel, EntropyExplorer, graphics, stats, |
|
27 |
- grDevices, pheatmap, utils, qvalue, |
|
28 |
- WGCNA, ReactomePA |
|
29 |
-Maintainer: Xiaowen Chen <Xiaowen.Chen@jax.org> |
|
30 |
-Author: Xiaowen Chen [aut, cre], Haitham Ashoor [aut], |
|
31 |
- Ryan Musich [aut], Jiahui Wang [aut], Sheng Li [aut] |
|
33 |
+ data.table, |
|
34 |
+ doParallel, |
|
35 |
+ EntropyExplorer, |
|
36 |
+ graphics, |
|
37 |
+ stats, |
|
38 |
+ grDevices, |
|
39 |
+ pheatmap, |
|
40 |
+ utils, |
|
41 |
+ qvalue, |
|
42 |
+ WGCNA, |
|
43 |
+ ReactomePA |
|
32 | 44 |
Encoding: UTF-8 |
33 |
-LazyData: true |
|
34 | 45 |
RoxygenNote: 6.0.1 |
35 |
-Suggests: knitr,clusterProfiler,ggfortify,org.Hs.eg.db, |
|
46 |
+Suggests: |
|
47 |
+ knitr, |
|
48 |
+ clusterProfiler, |
|
49 |
+ ggfortify, |
|
50 |
+ org.Hs.eg.db, |
|
36 | 51 |
rmarkdown |
37 | 52 |
VignetteBuilder: knitr |
38 | 53 |
BuildVignettes: TRUE |
54 |
+URL: https://github.com/TheJacksonLaboratory/epihet |
|
55 |
+BugReports: https://github.com/TheJacksonLaboratory/epihet/issues |
... | ... |
@@ -1,7 +1,7 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 | 3 |
Date: 2018-04-10 |
4 |
-Version: 0.99.2 |
|
4 |
+Version: 0.99.3 |
|
5 | 5 |
Authors@R: c(person("Xiaowen", "Chen", email = "Xiaowen.Chen@jax.org", |
6 | 6 |
role = c("aut", "cre")),person("Haitham", "Ashoor", |
7 | 7 |
role = c("aut")),person("Ryan", "Musich", role = c("aut")), |
... | ... |
@@ -1,7 +1,7 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 | 3 |
Date: 2018-04-10 |
4 |
-Version: 0.99.1 |
|
4 |
+Version: 0.99.2 |
|
5 | 5 |
Authors@R: c(person("Xiaowen", "Chen", email = "Xiaowen.Chen@jax.org", |
6 | 6 |
role = c("aut", "cre")),person("Haitham", "Ashoor", |
7 | 7 |
role = c("aut")),person("Ryan", "Musich", role = c("aut")), |
... | ... |
@@ -17,7 +17,7 @@ Description: epihet is an R-package that calculates the epigenetic |
17 | 17 |
created by calculating the differential heterogeneity of the samples. |
18 | 18 |
And we construct co-epihet network and perform network analysis. |
19 | 19 |
Depends: |
20 |
- R(>= 3.4),GenomicRanges, IRanges, S4Vectors,ggplot2,foreach,Rtsne, |
|
20 |
+ R(>= 3.5),GenomicRanges, IRanges, S4Vectors,ggplot2,foreach,Rtsne, |
|
21 | 21 |
igraph |
22 | 22 |
License: Artistic-2.0 |
23 | 23 |
biocViews: |
... | ... |
@@ -1,7 +1,7 @@ |
1 | 1 |
Package: epihet |
2 | 2 |
Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
3 | 3 |
Date: 2018-04-10 |
4 |
-Version: 0.99.0 |
|
4 |
+Version: 0.99.1 |
|
5 | 5 |
Authors@R: c(person("Xiaowen", "Chen", email = "Xiaowen.Chen@jax.org", |
6 | 6 |
role = c("aut", "cre")),person("Haitham", "Ashoor", |
7 | 7 |
role = c("aut")),person("Ryan", "Musich", role = c("aut")), |
... | ... |
@@ -4,8 +4,7 @@ Date: 2018-04-10 |
4 | 4 |
Version: 0.99.0 |
5 | 5 |
Authors@R: c(person("Xiaowen", "Chen", email = "Xiaowen.Chen@jax.org", |
6 | 6 |
role = c("aut", "cre")),person("Haitham", "Ashoor", |
7 |
- role = c("aut")),person("Ryan", "Musich", |
|
8 |
- email = "rjmusich@gmail.com",role = c("aut")), |
|
7 |
+ role = c("aut")),person("Ryan", "Musich", role = c("aut")), |
|
9 | 8 |
person("Jiahui","Wang",role = "aut"),person("Sheng", "Li", role = "aut")) |
10 | 9 |
Description: epihet is an R-package that calculates the epigenetic |
11 | 10 |
heterogeneity between cancer cells and/or normal cells. The functions |
... | ... |
@@ -18,19 +17,18 @@ Description: epihet is an R-package that calculates the epigenetic |
18 | 17 |
created by calculating the differential heterogeneity of the samples. |
19 | 18 |
And we construct co-epihet network and perform network analysis. |
20 | 19 |
Depends: |
21 |
- R(>= 3.3),GenomicRanges, IRanges, S4Vectors,ggplot2,foreach,Rtsne, |
|
20 |
+ R(>= 3.4),GenomicRanges, IRanges, S4Vectors,ggplot2,foreach,Rtsne, |
|
22 | 21 |
igraph |
23 | 22 |
License: Artistic-2.0 |
24 | 23 |
biocViews: |
25 | 24 |
DNAMethylation, Epigenetics, MethylSeq, Sequencing, Software |
26 | 25 |
Imports: |
27 | 26 |
data.table, doParallel, EntropyExplorer, graphics, stats, |
28 |
- grDevices, pheatmap,Rcpp, utils, qvalue, |
|
27 |
+ grDevices, pheatmap, utils, qvalue, |
|
29 | 28 |
WGCNA, ReactomePA |
30 |
-LinkingTo: Rcpp |
|
31 | 29 |
Maintainer: Xiaowen Chen <Xiaowen.Chen@jax.org> |
32 |
-Author: Xiaowen Chen [aut, cre], Haitham Ashoor [aut, cre], |
|
33 |
- Ryan Musich [aut, cre], Jiahui Wang [aut], Sheng Li [aut] |
|
30 |
+Author: Xiaowen Chen [aut, cre], Haitham Ashoor [aut], |
|
31 |
+ Ryan Musich [aut], Jiahui Wang [aut], Sheng Li [aut] |
|
34 | 32 |
Encoding: UTF-8 |
35 | 33 |
LazyData: true |
36 | 34 |
RoxygenNote: 6.0.1 |
... | ... |
@@ -24,7 +24,7 @@ License: Artistic-2.0 |
24 | 24 |
biocViews: |
25 | 25 |
DNAMethylation, Epigenetics, MethylSeq, Sequencing, Software |
26 | 26 |
Imports: |
27 |
- data.table, doMC, EntropyExplorer, graphics, stats, |
|
27 |
+ data.table, doParallel, EntropyExplorer, graphics, stats, |
|
28 | 28 |
grDevices, pheatmap,Rcpp, utils, qvalue, |
29 | 29 |
WGCNA, ReactomePA |
30 | 30 |
LinkingTo: Rcpp |
... | ... |
@@ -34,7 +34,7 @@ Author: Xiaowen Chen [aut, cre], Haitham Ashoor [aut, cre], |
34 | 34 |
Encoding: UTF-8 |
35 | 35 |
LazyData: true |
36 | 36 |
RoxygenNote: 6.0.1 |
37 |
-Suggests: knitr,clusterProfiler,doParallel,ggfortify, |
|
37 |
+Suggests: knitr,clusterProfiler,ggfortify,org.Hs.eg.db, |
|
38 | 38 |
rmarkdown |
39 | 39 |
VignetteBuilder: knitr |
40 | 40 |
BuildVignettes: TRUE |
1 | 1 |
new file mode 100755 |
... | ... |
@@ -0,0 +1,40 @@ |
1 |
+Package: epihet |
|
2 |
+Title: Determining Epigenetic Heterogeneity from Bisulfite Sequencing Data |
|
3 |
+Date: 2018-04-10 |
|
4 |
+Version: 0.99.0 |
|
5 |
+Authors@R: c(person("Xiaowen", "Chen", email = "Xiaowen.Chen@jax.org", |
|
6 |
+ role = c("aut", "cre")),person("Haitham", "Ashoor", |
|
7 |
+ role = c("aut")),person("Ryan", "Musich", |
|
8 |
+ email = "rjmusich@gmail.com",role = c("aut")), |
|
9 |
+ person("Jiahui","Wang",role = "aut"),person("Sheng", "Li", role = "aut")) |
|
10 |
+Description: epihet is an R-package that calculates the epigenetic |
|
11 |
+ heterogeneity between cancer cells and/or normal cells. The functions |
|
12 |
+ establish a pipeline that take in bisulfite sequencing data from multiple |
|
13 |
+ samples and use the data to track similarities and differences in |
|
14 |
+ epipolymorphism,proportion of discordantly methylated sequencing reads |
|
15 |
+ (PDR),and Shannon entropy values at epialleles that are shared between |
|
16 |
+ the samples.epihet can be used to perform analysis on the data by creating |
|
17 |
+ pheatmaps, box plots, PCA plots, and t-SNE plots. MA plots can also be |
|
18 |
+ created by calculating the differential heterogeneity of the samples. |
|
19 |
+ And we construct co-epihet network and perform network analysis. |
|
20 |
+Depends: |
|
21 |
+ R(>= 3.3),GenomicRanges, IRanges, S4Vectors,ggplot2,foreach,Rtsne, |
|
22 |
+ igraph |
|
23 |
+License: Artistic-2.0 |
|
24 |
+biocViews: |
|
25 |
+ DNAMethylation, Epigenetics, MethylSeq, Sequencing, Software |
|
26 |
+Imports: |
|
27 |
+ data.table, doMC, EntropyExplorer, graphics, stats, |
|
28 |
+ grDevices, pheatmap,Rcpp, utils, qvalue, |
|
29 |
+ WGCNA, ReactomePA |
|
30 |
+LinkingTo: Rcpp |
|
31 |
+Maintainer: Xiaowen Chen <Xiaowen.Chen@jax.org> |
|
32 |
+Author: Xiaowen Chen [aut, cre], Haitham Ashoor [aut, cre], |
|
33 |
+ Ryan Musich [aut, cre], Jiahui Wang [aut], Sheng Li [aut] |
|
34 |
+Encoding: UTF-8 |
|
35 |
+LazyData: true |
|
36 |
+RoxygenNote: 6.0.1 |
|
37 |
+Suggests: knitr,clusterProfiler,doParallel,ggfortify, |
|
38 |
+ rmarkdown |
|
39 |
+VignetteBuilder: knitr |
|
40 |
+BuildVignettes: TRUE |