% Generated by roxygen2: do not edit by hand % Please edit documentation in R/AllClasses.R \docType{class} \name{deSet-class} \alias{deSet-class} \title{The differential expression class (deSet)} \description{ The \code{deSet} class extends the \code{\link{ExpressionSet}} class. While the \code{ExpressionSet} class contains information about the experiment, the \code{deSet} class contains both experimental information and additional information relevant for differential expression analysis, explained below in Slots. } \section{Slots}{ \describe{ \item{\code{null.model}}{\code{formula}: contains the adjustment variables in the experiment. The null model is used for comparison when fitting the full model.} \item{\code{full.model}}{\code{formula}: contains the adjustment variables and the biological variables of interest.} \item{\code{null.matrix}}{\code{matrix}: the null model as a matrix.} \item{\code{full.matrix}}{\code{matrix}: the full model as a matrix.} \item{\code{individual}}{\code{factor}: contains information on which sample is from which individual in the experiment.} \item{\code{qvalueObj}}{\code{S3 object}: containing \code{qvalue} object. See \code{\link{qvalue}} for additional details.} }} \note{ See \code{\link{ExpressionSet}} for additional slot information. } \section{Methods}{ \describe{ \item{\code{as(ExpressionSet, "deSet")}}{Coerce objects of \code{ExpressionSet} to \code{deSet}.} \item{\code{lrt(deSet, ...)}}{Performs a generalized likelihood ratio test using the full and null models.} \item{\code{odp(deSet, ...)}}{Performs the optimal discovery procedure, which is a new approach for optimally performing many hypothesis tests in a high-dimensional study.} \item{\code{kl_clust(deSet, ...)}}{An implementation of mODP that assigns genes to modules based off of the Kullback-Leibler distance.} \item{\code{fit_models(deSet, ...)}}{Fits a linear model to each gene by method of least squares.} \item{\code{apply_qvalue(deSet, ...)}}{Applies \code{\link{qvalue}} function.} \item{\code{apply_snm(deSet, ...)}}{Applies surpervised normalization of microarrays (\code{\link{snm}}) on gene expression data.} \item{\code{apply_sva(deSet, ...)}}{Applies surrogate variable analysis (\code{\link{sva}}).} \item{\code{fullMatrix(deSet)}}{Access and set full matrix.} \item{\code{nullMatrix(deSet)}}{Access and set null matrix.} \item{\code{fullModel(deSet)}}{Access and set full model.} \item{\code{nullModel(deSet)}}{Access and set null model.} \item{\code{individual(deSet)}}{Access and set individual slot.} \item{\code{qvalueObj(deSet)}}{Access \code{qvalue} object. See \code{\link{qvalue}}.} \item{\code{validObject(deSet)}}{Check validity of \code{deSet} object.} } } \author{ John Storey, Jeffrey Leek, Andrew Bass }