Package: diffHic Version: 1.39.1 Date: 2024-12-16 Title: Differential Analysis of Hi-C Data Author: Aaron Lun, Gordon Smyth Maintainer: Aaron Lun <infinite.monkeys.with.keyboards@gmail.com>, Gordon Smyth <smyth@wehi.edu.au>, Hannah Coughlin <coughlin.h@wehi.edu.au> Depends: R (>= 3.5), GenomicRanges, InteractionSet, SummarizedExperiment Imports: Rsamtools, Rhtslib, Biostrings, BSgenome, rhdf5, edgeR, limma, csaw, locfit, methods, IRanges, S4Vectors, GenomeInfoDb, BiocGenerics, grDevices, graphics, stats, utils, Rcpp, rtracklayer Suggests: BSgenome.Ecoli.NCBI.20080805, Matrix, testthat biocViews: MultipleComparison, Preprocessing, Sequencing, Coverage, Alignment, Normalization, Clustering, HiC Description: Detects differential interactions across biological conditions in a Hi-C experiment. Methods are provided for read alignment and data pre-processing into interaction counts. Statistical analysis is based on edgeR and supports normalization and filtering. Several visualization options are also available. License: GPL-3 NeedsCompilation: yes LinkingTo: Rhtslib (>= 1.13.1), Rcpp SystemRequirements: C++, GNU make