git-svn-id: file:///home/git/hedgehog.fhcrc.org/bioconductor/trunk/madman/Rpacks/crlmm@49898 bc3139a8-67e5-0310-9ffc-ced21a209358
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@@ -23,6 +23,10 @@ been generated by the \code{crlmmCopynumber} function. |
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\usage{ |
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CA(object, ...) |
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CB(object, ...) |
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+nuA(object) |
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+nuB(object) |
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+phiA(object) |
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+phiB(object) |
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totalCopynumber(object,...) |
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} |
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@@ -37,15 +41,31 @@ totalCopynumber(object,...) |
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\details{ |
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+ At polymorphic markers, nuA and nuB provide the intercept |
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+ coefficient (the estimated background intensity) for the A and |
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+ B alleles, respectively. phiA and phiB provide the slope |
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+ coefficients for the A and B alleles, respectively. |
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+ |
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+ At nonpolymorphic markers, nuB and phiB are 'NA'. |
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+ |
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These functions can be used to tranlate the normalized |
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intensities to the copy number scale. Plotting the copy |
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number estimates as a function of physical position can be |
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used to guide downstream algorithms that smooth, as well as to |
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assess possible mosaicism. |
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+ |
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} |
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+ |
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\value{ |
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- A matrix of allele-specific or total copy number estimates. |
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+ |
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+ nu[A/B] and phi[A/B] return matrices of the intercept and |
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+ slope coefficients, respectively. |
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+ |
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+ CA and CB return matrices of allele-specific copy number. |
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+ |
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+ totalCopynumber returns a matrix of CA+CB. |
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+ |
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} |
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\seealso{ |