## IMPORTANT - move IRanges and oligoClasses back to Suggests? BC moved them to Depends just to get rid of annoying warnings while transitioning. ##################################### ### FOR CRLMM ##################################### - Add RS ids to annotation packages - Allele plots - M v S plots R. Scharpf - harmonize CNSet and FFSet classes use-cases: - import S3 classes and methods from ff in the NAMESPACE (but this would require installing ff) - initialization of FFSet (can it extend CNSet directly?) - subsetting of FFSet objects - snp-specific plots (FFSet or CNSet) - batch effect plots (FFSet or CNSet) - with cbs - with hmm - ff support for Illumina platforms - fix all the install warnings - add README file to inst/scripts to outline the vignettes Vignettes: copynumber_SmallData.Rnw (Affy 5.0 or Affy 6.0. Fewer than 300 samples) copynumber_BigData.Rnw (Affy 5.0 or Affy 6.0. 300+ samples. Requires ff package.) illumina_copynumber_small.Rnw (Illumina platforms. Fewer than 300 samples) illumina_copynumber_big.Rnw (Illumina platforms. More than 300 samples. Requires ff package.) - documentation for FFSet class/methods - bias adjustment for X chromosome - where to find examples downstream (smoothing) - downstream objects should be similar whether using ff or regular matrices ## this should be moved to vanillaice ## - Allow a copy-neutral ROH state by not having an equal prior on the ## ellipses. For instance, ## ## normal state: 1/4 AA, 1/2 AB, 1/4 BB ## ## copy-neutral ROH: (1-epsilon)/2 AA, epsilon AB, (1-epsilon)/2 ## BB B Carvalho - crlmm should return results in CHP files (still can't write CHP files) - add parallel support (normalization and summarization)