# cliProfiler Author: You Zhou, Kathi Zarnack --- # Introduction Cross-linking immunoprecipitation (CLIP) is a technique that combines UV cross-linking and immunoprecipitation to analyse protein-RNA interactions or to pinpoint RNA modifications (e.g. m6A). CLIP-based methods, such as iCLIP and eCLIP, allow precise mapping of RNA modification sites or RNA-binding protein (RBP) binding sites on a genome-wide scale. These techniques help us to unravel post-transcriptional regulatory networks. In order to make the visualization of CLIP data easier, we develop `r Biocpkg("cliProfiler")` package. The `r Biocpkg("cliProfiler")` includes seven functions which allow users easily make different profile plots. The `r Biocpkg("cliProfiler")` package is available at [https://bioconductor.org](https://bioconductor.org) and can be installed via `BiocManager::install`: ```{r BiocManager, eval=FALSE} if (!require("BiocManager")) install.packages("BiocManager") BiocManager::install("cliProfiler") ``` A package only needs to be installed once. Load the package into an R session with ```{r initialize, results="hide", warning=FALSE, message=FALSE} library(cliProfiler) ``` # How to use it Documentation (vignette and user manual) is available at the **cliProfiler** Bioconductor landing page at http://bioconductor.org/packages/cliProfiler.