\name{BS.chr22} \alias{BS.chr22} \docType{data} \title{ Whole-genome bisulfite sequencing for chromosome 22 from Lister et al. } \description{ This dataset represents chromosome 22 from the IMR90 cell line sequenced in Lister et al. Only CpG methylation are included (there were very few non-CpG loci). The two samples are two different extractions from the same cell line (ie. technical replicates), and are pooled in the analysis in the original paper. } \usage{data(BS.chr22)} \format{ An object of class \code{BSseq}. } \details{ All coordinates are in hg18. } \source{ Obtained from \url{http://neomorph.salk.edu/human_methylome/data.html} specifically the files \url{mc_imr90_r1.tar.gz} and \url{mc_imr90_r2.tar.gz}. A script which downloads these files and constructs the \code{BS.chr22} object may be found in \file{inst/scripts/get_BS.chr22.R}, see the example. } \references{ R Lister et al. \emph{Human DNA methylomes at base resolution show widespread epigenomic differences}. Nature (2009) 462, 315-322. } \examples{ data(BS.chr22) BS.chr22 script <- system.file("scripts", "get_BS.chr22.R", package = "bsseq") script readLines(script) } \keyword{datasets}