Package: awst
Title: Asymmetric Within-Sample Transformation
Version: 1.11.0
Authors@R: 
    c(person(given = "Davide",
                family = "Risso",
                role = c("aut", "cre", "cph"),
                email = "risso.davide@gmail.com",
                comment = c(ORCID = "0000-0001-8508-5012")),
        person(given = "Stefano",
               family = "Pagnotta",
               role = c("aut", "cph"),
               email = "smpagnotta@gmail.com",
               comment = c(ORCID = "0000-0002-8298-9777")))
Description:
    We propose an Asymmetric Within-Sample Transformation (AWST)
    to regularize RNA-seq read counts and reduce the effect of noise
    on the classification of samples. AWST comprises two main steps:
    standardization and smoothing. These steps transform gene expression data to
    reduce the noise of the lowly expressed features, which suffer from
    background effects and low signal-to-noise ratio, and the influence of the
    highly expressed features, which may be the result of amplification bias
    and other experimental artifacts.
License: MIT + file LICENSE
Encoding: UTF-8
RoxygenNote: 7.1.1
URL: https://github.com/drisso/awst
BugReports: https://github.com/drisso/awst/issues
Imports:
    stats,
    methods,
    SummarizedExperiment
Suggests: 
    airway,
    ggplot2,
    testthat,
    EDASeq,
    knitr,
    BiocStyle,
    RefManageR,
    sessioninfo,
    rmarkdown
biocViews:
    Normalization,
    GeneExpression,
    RNASeq,
    Software,
    Transcriptomics,
    Sequencing,
    SingleCell
VignetteBuilder: knitr