(the [Sassolungo](https://en.wikipedia.org/wiki/Langkofel) mountain in the Dolomites)
*alpine* is an R/Bioconductor package for modeling and correcting fragment
sequence bias for RNA-seq transcript abundance estimation. In
particular, it is the first method of its kind to take into account
sample-specific dependence of RNA-seq fragments on their GC content.
An example workflow can be found in `vignettes/alpine.Rmd`, or by typing:
*alpine* is designed for un-stranded paired-end RNA-seq data.
A paper explaining the *alpine* methods was published in December 2016: