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@@ -4,12 +4,16 @@ Title: Mutational Signature Estimation for Single Samples |
| 4 | 4 |
Version: 0.99.0 |
| 5 | 5 |
Author: Franziska Schumann <franziska.schumann@student.hpi.de> |
| 6 | 6 |
Maintainer: Franziska Schumann <franziska.schumann@student.hpi.de> |
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-Description: More about what it does (maybe more than one line) |
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- Use four spaces when indenting paragraphs within the Description. |
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-License: GPL (>=2) |
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+Description: Single sample estimation of exposure to mutational signatures. |
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+ Exposures to known mutational signatures are estimated for single samples, |
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| 9 |
+ based on quadratic programming algorithms. Bootstrapping the input |
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+ mutational catalogues provides estimations on the stability of these |
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+ exposures. The effect of the sequence composition of mutational context |
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+ can be taken into account by normalising the catalogues. |
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+License: BSD_3_clause + file LICENSE |
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| 10 | 14 |
Encoding: UTF-8 |
| 11 | 15 |
Depends: |
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- R (>= 3.4.4) |
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+ R (>= 3.4) |
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| 13 | 17 |
biocViews: |
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Imports: |
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quadprog (>= 1.5-5), |
| ... | ... |
@@ -25,11 +29,11 @@ Suggests: |
| 25 | 29 |
rtracklayer, |
| 26 | 30 |
SummarizedExperiment, |
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knitr, |
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- rmarkdown |
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+ rmarkdown |
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| 29 | 33 |
VignetteBuilder: knitr |
| 30 | 34 |
BiocViews: |
| 31 |
-BugReports: Link(s) to github (issues) |
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| 32 |
-URL: probably github |
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+BugReports: https://github.com/bihealth/SigsPack/issues |
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+URL: https://github.com/bihealth/SigsPack |
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| 33 | 37 |
Collate: |
| 34 | 38 |
bootstrap_mut_catalogues.R |
| 35 | 39 |
cosmicSigs.R |
| ... | ... |
@@ -43,4 +47,4 @@ Collate: |
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summarize_exposures.R |
| 44 | 48 |
vcf2mut_cat.R |
| 45 | 49 |
RoxygenNote: 6.1.1 |
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-LazyData: TRUE |
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| 50 |
+LazyData: true |
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@@ -35,7 +35,7 @@ BiocManager::install("SigsPack")
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Or install the development version of the package from Github |
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```{r, eval = FALSE}
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-devtools::install_github(“fefschumann/SigsPack”) |
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+devtools::install_github("fefschumann/SigsPack")
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``` |
| 40 | 40 |
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And then load the package into your R session. |
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@@ -146,4 +146,4 @@ if (require(BSgenome.Hsapiens.UCSC.hg19)){
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## sessionInfo |
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```{r}
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sessionInfo() |
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-``` |
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\ No newline at end of file |
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+``` |
