Package: SMITE Type: Package Title: Significance-based Modules Integrating the Transcriptome and Epigenome Version: 1.31.0 Date: 2021-11-21 Author: Neil Ari Wijetunga, Andrew Damon Johnston, John Murray Greally Maintainer: Neil Ari Wijetunga <nawijet@gmail.com>, Andrew Damon Johnston <Andrew.Johnston@med.einstein.yu.edu> Description: This package builds on the Epimods framework which facilitates finding weighted subnetworks ("modules") on Illumina Infinium 27k arrays using the SpinGlass algorithm, as implemented in the iGraph package. We have created a class of gene centric annotations associated with p-values and effect sizes and scores from any researchers prior statistical results to find functional modules. License: GPL (>=2) Depends: R (>= 3.5), GenomicRanges Imports: scales, plyr, Hmisc, AnnotationDbi, org.Hs.eg.db, ggplot2, reactome.db, KEGGREST, BioNet, goseq, methods, IRanges, igraph, Biobase,tools, S4Vectors, geneLenDataBase, grDevices, graphics, stats, utils Suggests: knitr, rmarkdown VignetteBuilder: knitr biocViews: ImmunoOncology, DifferentialMethylation, DifferentialExpression, SystemsBiology, NetworkEnrichment,GenomeAnnotation,Network, Sequencing, RNASeq, Coverage URL: https://github.com/GreallyLab/SMITE BugReports: https://github.com/GreallyLab/SMITE/issues NeedsCompilation: no