// ========================================================================== // SeqAn - The Library for Sequence Analysis // ========================================================================== // Copyright (c) 2006-2018, Knut Reinert, FU Berlin // All rights reserved. // // Redistribution and use in source and binary forms, with or without // modification, are permitted provided that the following conditions are met: // // * Redistributions of source code must retain the above copyright // notice, this list of conditions and the following disclaimer. // * Redistributions in binary form must reproduce the above copyright // notice, this list of conditions and the following disclaimer in the // documentation and/or other materials provided with the distribution. // * Neither the name of Knut Reinert or the FU Berlin nor the names of // its contributors may be used to endorse or promote products derived // from this software without specific prior written permission. // // THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" // AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE // IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE // ARE DISCLAIMED. IN NO EVENT SHALL KNUT REINERT OR THE FU BERLIN BE LIABLE // FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL // DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR // SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER // CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT // LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY // OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH // DAMAGE. // // ========================================================================== // Author: Rene Rahn <rene.rahn@fu-berlin.de> // ========================================================================== // Implements the dynamic gap model published in "Dynamic Gaps Selector: // A Smith Waterman Sequence Alignment Algorithm with Affine Gap Model // Optimization" by Gianvito Urgese et al. // ========================================================================== #ifndef INCLUDE_SEQAN_ALIGN_DP_CELL_DYNAMIC_H_ #define INCLUDE_SEQAN_ALIGN_DP_CELL_DYNAMIC_H_ namespace seqan { // ============================================================================ // Forwards // ============================================================================ // ---------------------------------------------------------------------------- // Metafunction GetFlagMaskType // ---------------------------------------------------------------------------- namespace impl { namespace dp_cell { template <typename TScoreValue> struct FlagMaskType { using Type = typename If<Is<SimdVectorConcept<TScoreValue> >, TScoreValue, uint8_t>::Type; }; } // namespace dp_cell } // namespace impl // ============================================================================ // Tags, Classes, Enums // ============================================================================ enum DynamicGapsMask { MASK_VERTICAL_GAP = 1, MASK_HORIZONTAL_GAP = 2 }; // ---------------------------------------------------------------------------- // Class DPCell [DynamicGaps] // ---------------------------------------------------------------------------- // The specialization for linear gap cost function. // It solely stores the maximal score. template <typename TScoreValue> class DPCell_<TScoreValue, DynamicGaps> { public: using TFlagMaskType = typename impl::dp_cell::FlagMaskType<TScoreValue>::Type; TScoreValue _score = DPCellDefaultInfinity<DPCell_>::VALUE; TFlagMaskType _flagMask = TFlagMaskType(); DPCell_() = default; // Copy c'tor. DPCell_(DPCell_ const & other) : _score(other._score), _flagMask(other._flagMask) {} // Move c'tor. DPCell_(DPCell_ && other) : DPCell_() { swap(*this, other); } // Construct with score. DPCell_(TScoreValue const & pScore) : _score(pScore) {} // Assignment and move operator. DPCell_& operator=(DPCell_ other) { swap(*this, other); return *this; } // Assignment of score. DPCell_ & operator=(TScoreValue const & score) { _score = score; return *this; } ~DPCell_() = default; }; // ============================================================================ // Metafunctions // ============================================================================ template <typename TCell, typename TBoolV, typename TBoolH> struct SetGapExtension; template <typename TScoreValue> struct SetGapExtension<DPCell_<TScoreValue, DynamicGaps>, False, False> { static const char VALUE = 0; }; template <typename TScoreValue> struct SetGapExtension<DPCell_<TScoreValue, DynamicGaps>, False, True> { static const char VALUE = MASK_HORIZONTAL_GAP; }; template <typename TScoreValue> struct SetGapExtension<DPCell_<TScoreValue, DynamicGaps>, True, False> { static const char VALUE = MASK_VERTICAL_GAP; }; template <typename TScoreValue> struct SetGapExtension<DPCell_<TScoreValue, DynamicGaps>, True, True> { static const char VALUE = MASK_HORIZONTAL_GAP | MASK_VERTICAL_GAP; }; // ============================================================================ // Functions // ============================================================================ template <typename TScoreValue, typename TFlag> inline void _setBit(DPCell_<TScoreValue, DynamicGaps> & cell, TFlag const & /*flag*/, DynamicGapExtensionVertical const & /*tag*/) { SEQAN_IF_CONSTEXPR (IsSameType<TFlag, True>::VALUE) cell._flagMask |= MASK_VERTICAL_GAP; else cell._flagMask &= ~MASK_VERTICAL_GAP; } template <typename TScoreValue, typename TFlag> inline void _setBit(DPCell_<TScoreValue, DynamicGaps> & cell, TFlag const & /*flag*/, DynamicGapExtensionHorizontal const & /*tag*/) { SEQAN_IF_CONSTEXPR (IsSameType<TFlag, True>::VALUE) cell._flagMask |= MASK_HORIZONTAL_GAP; else cell._flagMask &= ~MASK_HORIZONTAL_GAP; } template <typename TScoreValue, typename TSpec> inline SEQAN_FUNC_ENABLE_IF(Not<Is<SimdVectorConcept<TScoreValue> > >,bool) isGapExtension(DPCell_<TScoreValue, DynamicGaps> const & cell, TSpec const & /*spec*/) { SEQAN_IF_CONSTEXPR (IsSameType<TSpec, DynamicGapExtensionHorizontal>::VALUE) return cell._flagMask & MASK_HORIZONTAL_GAP; else return cell._flagMask & MASK_VERTICAL_GAP; } template <typename TScoreValue, typename TSpec> inline SEQAN_FUNC_ENABLE_IF(Is<SimdVectorConcept<TScoreValue> >,TScoreValue) isGapExtension(DPCell_<TScoreValue, DynamicGaps> const & cell, TSpec const & /*spec*/) { return blend(cell._flagMask & createVector<TScoreValue>(MASK_VERTICAL_GAP), cell._flagMask & createVector<TScoreValue>(MASK_HORIZONTAL_GAP), createVector<TScoreValue>(IsSameType<TSpec, DynamicGapExtensionHorizontal>::VALUE)); } template <typename TScoreValue, typename TFlagV, typename TFlagH> inline SEQAN_FUNC_ENABLE_IF(Not<Is<SimdVectorConcept<TScoreValue> > >, void) setGapExtension(DPCell_<TScoreValue, DynamicGaps> & cell, TFlagV const & /*vert*/, TFlagH const & /*hori*/) { cell._flagMask = SetGapExtension<DPCell_<TScoreValue, DynamicGaps>, TFlagV, TFlagH>::VALUE; } template <typename TScoreValue, typename TFlagV, typename TFlagH> inline SEQAN_FUNC_ENABLE_IF(Is<SimdVectorConcept<TScoreValue> >, void) setGapExtension(DPCell_<TScoreValue, DynamicGaps> & cell, TFlagV const & /*vert*/, TFlagH const & /*hori*/, TScoreValue const & cmp) { cell._flagMask = blend(cell._flagMask, createVector<TScoreValue>(SetGapExtension<DPCell_<TScoreValue, DynamicGaps>, TFlagV, TFlagH>::VALUE), cmp); } // ---------------------------------------------------------------------------- // Function operator<() // ---------------------------------------------------------------------------- // Needed for banded chain alignment for the std::set. template <typename TScoreValueLeft, typename TScoreValueRight> inline bool operator<(DPCell_<TScoreValueLeft, DynamicGaps> const & left, DPCell_<TScoreValueRight, DynamicGaps> const & right) { return left._score < right._score; } template <typename TScoreValue> inline void swap(DPCell_<TScoreValue, DynamicGaps> & lhs, DPCell_<TScoreValue, DynamicGaps> & rhs) { std::swap(lhs._score, rhs._score); std::swap(lhs._flagMask, rhs._flagMask); } } // namespace seqan #endif // INCLUDE_SEQAN_ALIGN_DP_CELL_DYNAMIC_H_