# ProteoDisco  []()  # Introduction ProteoDisco is an R package to facilitate proteogenomics studies. It houses functions to create customized (variant) protein databases based on user-submitted genomic variants, splice-junctions, fusion genes and manual transcript sequences. The flexible workflow can be adopted to suit a myriad of research and experimental settings. ## Citation van de Geer, Wesley S. and van Riet, Job and van de Werken, Harmen J. G. [ProteoDisco: a flexible R approach to generate customized protein databases for extended search space of novel and variant proteins in proteogenomic studies](https://doi.org/10.1093/bioinformatics/btab809). *Bioinformatics* **2022** 38(5), 1437–1439. # Installation The latest development version can be installed directly from GitHub: ```R # Require/install devtools package if not already installed. if (!require("devtools")) install.packages("devtools", repos = "http://cran.r-project.org") # Install ProteoDisco from GitHub. devtools::install_github(repo = "ErasmusMC-CCBC/ProteoDisco") library(ProteoDisco) ``` Or from BioConductor: ```R if (!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("ProteoDisco") ``` # Usage Please view the vignettes for instructions and tutorials on how to use this package. ```R browseVignettes("ProteoDisco") ```