Package: OncoSimulR Type: Package Title: Simulation of cancer progresion with order restrictions Version: 1.2.0 Date: 2014-07-14 Author: Ramon Diaz-Uriarte. Maintainer: Ramon Diaz-Uriarte <rdiaz02@gmail.com> Description: Functions for simulating and plotting cancer progression data, including drivers and passengers, and allowing for order restrictions. Simulations use continuous-time models (based on Bozic et al., 2010 and McFarland et al., 2013) and fitness functions account for possible restrictions in the order of accumulation of mutations. biocViews: BiologicalQuestion, SomaticMutation License: GPL (>= 3) Depends: R (>= 3.1.0) Imports: Rcpp (>= 0.11.1), parallel, data.table, graph, Rgraphviz Suggests: BiocStyle, knitr, Oncotree LinkingTo: Rcpp VignetteBuilder: knitr SystemRequirements: C++11