\name{doEnrichment} \alias{doEnrichment} \title{Runs enrichment analysis of contributing genes} \usage{ doEnrichment(compSel, chip, onto, hgCutoff, cond, universe, path, db, pack.annot.EID, Slist, it, cutoff, entrez2symbol) } \arguments{ \item{compSel}{A list containing three elements \describe{ \item{compSel}{the projection values of contributing genes that were selected based on their absolute projection} \item{compSel_neg}{the projection values of contributing genes that have negative projections} \item{compSel_pos}{the projection values of contributing genes that have positive projections}}} \item{chip}{The annotation package} \item{onto}{A string specifying the GO ontology to use. Must be one of 'BP', 'CC', or 'MF', see \code{\link[Category:GOHyperGParams-class]{GOHyperGParams}}. Only used when argument \code{db} is 'GO'.} \item{hgCutoff}{The p-value threshold} \item{cond}{A logical indicating whether the calculation should conditioned on the GO structure, see \code{\link[Category:GOHyperGParams-class]{GOHyperGParams}}.} \item{universe}{The universe for the hypergeometric tests, see \code{\link[Category:GOHyperGParams-class]{GOHyperGParams}}.} \item{path}{The path where results will be saved} \item{db}{The used database to use ('GO' or 'KEGG')} \item{pack.annot.EID}{The name of the environment of the annotation package containing the annotation for Entrez Gene.} \item{Slist}{The list of gene projections across all components} \item{it}{The index of the component} \item{cutoff}{The threshold applied on the gene projections, used to select the contributing genes} \item{entrez2symbol}{A vector of all gene Symbols involved in the analysis indexed by their Entrez Gene IDs. It is only used when \code{annotation(params)} is empty, and allows to associate gene sets to Symbols.} } \value{ Object of class \code{GOHyperGResult-class} } \description{ doEnrichment This internal function is called by \code{hypergeoAn} and runs hypergeometric tests through function \code{hyperGTest} to associate the contributing genes of a component to gene sets. } \author{ Anne Biton } \keyword{internal}