\name{writeGenes} \alias{writeGenes} \title{Description of features using package \code{biomaRt}.} \usage{ writeGenes(data, filename = NULL, mart = useMart(biomart = "ensembl", dataset = "hsapiens_gene_ensembl"), typeId = "hgnc_symbol", typeRetrieved = NULL, sortBy = NULL, sortAbs = TRUE, colAnnot = NULL, decreasing = TRUE, highlight = NULL, caption = "") } \arguments{ \item{data}{Either a data.frame whose rownames or one of its columns contain the IDs to be annotated, or a vector of IDs.} \item{filename}{The name of the HTML file where gene annotations are written.} \item{mart}{Output of function \code{useMart} from package \code{biomaRt}.} \item{typeId}{The type of IDs available in \code{data}, in the biomaRt way (type \code{listFilters(mart)} to choose one).} \item{typeRetrieved}{The descriptors uses to annotate the features of \code{data} (type \code{listAttributes(mart)} to choose one or several).} \item{sortBy}{Name of a column of \code{data} used to order the output.} \item{sortAbs}{If TRUE absolute value of column \code{sortBy} is used to order the output.} \item{colAnnot}{The column containing the IDs to be annotated, if NULL or missing and argument \code{data} is a data.frame, then rownames of \code{data} must contain the IDs.} \item{decreasing}{If TRUE, the output is sorted by decreasing values of the \code{sortBy} column} \item{highlight}{IDs to be displayed in colour red in the returned table} \item{caption}{A title for the HTML table} } \value{ This function returns a data.frame which contains annotations of the input data. } \description{ This function annotates IDs (typically gene IDs) provided by the user and returns an html file with their description. } \details{ \code{"hgnc_symbol", "ensembl_gene_id", "description", "chromosome_name", "start_position", "end_position", "band"}, and \code{"strand"}, are automatically added to the list of fields available in argument \code{typeRetrieved} queried on biomaRt. The web-links to www.genecards.org and www.proteinatlas.org are automatically added in the columns of the output respectively corresponding to \code{hgnc_symbol} and \code{ensembl_gene_id}. } \examples{ if (interactive()) { ## define the database to be used mart <- useMart(biomart="ensembl", dataset="hsapiens_gene_ensembl") ### Describe: ## a set of hgnc symbols with default descriptions (typeRetrieved=NULL) genes <- c("TOP2A","E2F3","E2F1","CDK1","CDC20","MKI67") writeGenes(data=genes, filename="foo", mart=mart, typeId = "hgnc_symbol") ## a data.frame indexed by hngc symbols, sort output according to column "values", add a title to the HTML output datagenes <- data.frame(values=rnorm(6),row.names = genes) writeGenes(data=datagenes, filename="foo", sortBy = "values", caption = "Description of some proliferation genes.") ## a set of Entrez Gene IDs with default descriptions genes <- c("7153","1871","1869","983","991","4288") writeGenes(data=genes, filename="foo", mart=mart, typeId = "entrezgene") } \dontrun{ ## add the GO category the genes belong to ## search in listAttributes(mart)[,1] which filter correspond to the Gene Ontology -> "go_id" writeGenes(data=genes, filename="foo", mart=mart, typeId = "entrezgene", typeRetrieved = "go_id") } } \author{ Anne Biton } \seealso{ \code{\link[biomaRt]{getBM}}, \code{\link[biomaRt]{listFilters}}, \code{\link[biomaRt]{listAttributes}}, \code{\link[biomaRt]{useMart}} }