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\name{addGenesToGoReport}
\alias{addGenesToGoReport}
\title{Add Symbol IDs to hyperGTest results}
\usage{
addGenesToGoReport(hgOver, universe,
db = c("GO", "KEGG"), onto = c("CC", "MF", "BP"),
annotation = NULL, entrez2symbol = NULL)
}
\arguments{
\item{hgOver}{Output of function
\code{\link[Category]{hyperGTest}}}
\item{universe}{A vector including all IDs on which
enrichment analysis was applied}
\item{db}{The database to use, default is c("GO","KEGG")}
\item{onto}{A string specifying the GO ontology to use.
Must be one of "BP", "CC", or "MF", see
\code{\link[Category:GOHyperGParams-class]{GOHyperGParams}}.
Only used when argument \code{db} is "GO".}
\item{annotation}{An annotation package}
\item{entrez2symbol}{A vector indexed by Entrez Gene ID
and filled with the corresponding Gene Symbols}
}
\value{
A data.frame containing the summary of the output of
function hyperGTest (\code{summary(hgOver)}) with an
additional column providing the gene Symbols included in
the significant gene sets.
}
\description{
Add gene Symbols contained in gene sets selected as
significant by \code{\link[Category]{hyperGTest}}
function
}
\details{
This function takes as inputs the outputs of
\code{\link[Category]{hyperGTest}} which takes Entrez
Gene IDs as inputs to perform the enrichment analysis.
The goal of this function is to select the Entrez Gene
IDs responsible for the significant enrichment of a given
gene set and annotate them in to gene Symbol IDs. When
the annotation package \code{annotation} was used to map
feature IDs to Entrez Gene ID, it can also be used here
to map Entrez and Symbol IDs. If the annotation package
was not used, but the Entrez Gene IDs were directly
provided to the hyperGtest function, \code{annotation} is
expected to be NULL and \code{entrez2symbol} must be
specified.
This function returns the outputs of function
\code{\link[Category]{hyperGTest}} which contain:
\describe{ \item{DB, ID, Term}{The database, the gene set
ID, and the gene Set name,} \item{P-value}{probability of
observing the number of genes annotated for the gene set
among the selected gene list, knowing the total number of
annotated genes among the universe}, \item{Expected
counts}{expected number of genes in the selected gene
list to be found at each tested category term/gene set,}
\item{Odds ratio}{odds ratio for each category term
tested which is an indicator of the level of enrichment
of genes within the list as against the universe,}
\item{Counts}{number of genes in the selected gene list
which are annotated for the gene set,} \item{Size}{number
of genes from the universe annotated for the gene set.}}
}
\author{
Anne Biton
}
\seealso{
\code{\link[Category]{hyperGTest}},
\code{\link[Category:GOHyperGParams-class]{GOHyperGParams}}
}
\keyword{internal}
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