Name Mode Size
..
DataSummary.R 100644 0 kb
bubblePlot.R 100644 2 kb
cytoPath.R 100644 3 kb
metaHeatmap.R 100644 2 kb
pathwayAnalysis.R 100644 4 kb
pathwayList.R 100644 0 kb
sysdata.rda 100644 24 kb
README.md
# MetaPhOR Metabolic Pathway Analysis of RNA MetaPhOR was developed to enable users to assess metabolic dysregulation using transcriptomic-level data (RNA-sequencing and Microarray data) and produce publication-quality figures. A list of differentially expressed genes (DEGs), which includes fold change and p value, from DESeq2 or limma, can be used as input, with sample size for MetaPhOR, and will produce a data frame of scores for each KEGG pathway. These scores represent the magnitude and direction of transcriptional change within the pathway, along with estimated p-values.MetaPhOR then uses these scores to visualize metabolic profiles within and between samples through a variety of mechanisms, including: bubble plots, heatmaps, and pathway models.