Name Mode Size
Meta 040000
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data-raw 040000
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.DS_Store 100644 6 kb
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DESCRIPTION 100644 1 kb
NAMESPACE 100644 1 kb 100644 1 kb
# MetaPhOR Metabolic Pathway Analysis of RNA MetaPhOR was developed to enable users to assess metabolic dysregulation using transcriptomic-level data (RNA-sequencing and Microarray data) and produce publication-quality figures. A list of differentially expressed genes (DEGs), which includes fold change and p value, from DESeq2 or limma, can be used as input, with sample size for MetaPhOR, and will produce a data frame of scores for each KEGG pathway. These scores represent the magnitude and direction of transcriptional change within the pathway, along with estimated p-values.MetaPhOR then uses these scores to visualize metabolic profiles within and between samples through a variety of mechanisms, including: bubble plots, heatmaps, and pathway models.