Name Mode Size
..
BSBinAggregate.Rd 100755 3 kb
BSreadBiSeq.Rd 100755 2 kb
MIRA.Rd 100755 1 kb
SummarizedExperimentToDataTable.Rd 100644 3 kb
addMethPropCol.Rd 100644 1 kb
aggregateMethyl.Rd 100644 3 kb
bigBinDT1.Rd 100644 1 kb
bigBinDT2.Rd 100644 1 kb
binRegion.Rd 100755 2 kb
bsseqToDataTable.Rd 100644 1 kb
calcMIRAScore.Rd 100644 5 kb
exampleAnnoDT1.Rd 100644 0 kb
exampleAnnoDT2.Rd 100644 0 kb
exampleBSDT.Rd 100755 1 kb
exampleBSseqObj.Rd 100644 0 kb
exampleBins.Rd 100755 0 kb
exampleRegionSet.Rd 100755 1 kb
plotMIRAProfiles.Rd 100644 1 kb
plotMIRAScores.Rd 100755 1 kb
rbindNamedList.Rd 100644 2 kb
README.md
# MIRA (Methylation-based Inference of Regulatory Activity) [![Build Status](https://travis-ci.org/databio/MIRA.svg?branch=master)](https://travis-ci.org/databio/MIRA) The MIRA package aggregates DNA methylation across the genome for instances of a genomic feature like histone ChIP peaks, transcription factor ChIP peaks, or open chromatin regions in order to give a single signature and score for that feature, which may be used to infer regulatory activity. ### Installing MIRA MIRA may be installed from Github: ```{r} devtools::install_github("databio/MIRA") ``` or locally after downloading/cloning the source code: ```{r} install.packages("path/to/MIRA/directory", repos=NULL, type="source") ``` ### Learning how to use MIRA A couple of vignettes are included with the package. For an overview of the package see the "Getting Started" vignette. A more realistic example of how to use MIRA may be found in the "BiologicalApplication" vignette.