% Generated by roxygen2: do not edit by hand % Please edit documentation in R/get_fisher_info.R \name{get_fisher_info} \alias{get_fisher_info} \title{Perform Fisher's Exact test for edges in pathway} \usage{ get_fisher_info(edges, method) } \arguments{ \item{edges}{The set of eges to be analyzed; Although the intended use is for LINCS data overlaps, the function should work with any typical data object as long as it has columns labeled ("UP", "DOWN", "UK1_DK2", "DK1_UK2") that contain integer values.} \item{method}{The method to correct/adjust p-values for multiple testing. For available methods, type 'p.adjust.methods' into command promt and press enter.} } \value{ The input edge data.frame object with additional columns containing the results of the applied statistical test } \description{ Obtain a measure for strength and significance for the relationship (i.e. an edge) based on the concordance/discordance of UP-and-DOWN regulated genes shared by two different experimental gene-knockouts Intended for use within \code{\link{overlap_info}} } \examples{ ex.data <- data.frame("UP" = c(70,6), "DOWN" = c(8,20), "UK1_DK2" = c(4,47), "DK1_UK2" = c(3, 28)) overlaps <- get_fisher_info(ex.data, method = "BH") }