\name{beta.data} \alias{beta.data} \docType{data} \title{ Beta Data Of SNP Regressed on Causal Variables and Disease } \description{ Beta data are a matrix dataset consisting of 5 columns: cad, ldl, hdl, tg, and tc with 368 rows. } \usage{data("beta.data")} \format{ A data frame with 368 observations on the following 5 variables. \describe{ \item{\code{cad}}{a numeric vector} \item{\code{ldl}}{a numeric vector} \item{\code{hdl}}{a numeric vector} \item{\code{tg}}{a numeric vector} \item{\code{tc}}{a numeric vector} } } \details{ Beta data are a matrix consisting of regression coefficients of 368 SNPs on cad, ldl, hdl, tg, tc where \verb{cad} is coronary artery disease, \verb{ldl} is low-density lipoprotein cholesterol, \verb{hdl}, high-density lipoprotein cholesterol, \verb{tg},triglycerides and \verb{tc}, total cholesterol in plasma. These 368 SNPs were obtained by using \verb{mktable} from \bold{GWAS} meta-analyzed data. } \value{ A set of real regression coefficients of 368 SNPs on disease and causal variables. } \source{ http://csg.sph.umich.edu//abecasis/public/lipids2013/ \\http://www.cardiogramplusc4d.org/downloads/ } \references{ Willer CJ et al. Discovery and refinement of loci associated with lipid levels. Nat. Genet. 2013. doi:10.1038/ng.2797. \\Schunkert, H. et al. 2011. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet 43: 333-338.[online] \\Schunkert H, Konig IR, Kathiresan S, Reilly MP, Assimes TL, Holm H et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011 43: 333-338. } \examples{ data(beta.data) ## maybe str(beta.data) ; plot(beta.data) ... } \keyword{datasets}