# ExpoRiskR
ExpoRiskR is a Bioconductor package for **exposure‑aware multi‑omics integration**.
It provides a unified framework to quantify exposure perturbation effects, build exposure‑adjusted networks, and derive interpretable risk scores from integrated omics data.
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## Installation
Install the released version from **Bioconductor**:
```r
if (!requireNamespace("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("ExpoRiskR")
```
You can install the development version from GitHub:
```r
if (!requireNamespace("devtools", quietly = TRUE))
install.packages("devtools")
devtools::install_github("ppchaudhary/ExpoRiskR")
```
---
## Overview
ExpoRiskR enables:
- Exposure‑aware multi‑omics integration
- Exposure perturbation scoring
- Network construction adjusted for environmental effects
- Feature importance ranking
- Individual risk profiling
- Visualization tools for interpretable results
The package is designed to work seamlessly with **Bioconductor data structures** such as `SummarizedExperiment`.
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## Quick Example
```r
library(ExpoRiskR)
# Generate example data
data <- generate_dummy_exporisk()
# Align omics data
aligned <- align_omics(
data$omics,
data$metadata,
exposure_col = "exposure"
)
# Compute exposure perturbation score
scores <- compute_exposure_scores(aligned)
# Build exposure‑adjusted network
net <- build_exposure_network(scores)
plot_network(net)
```
---
## Documentation
Full tutorials and workflow examples are available in the package vignette:
```r
browseVignettes("ExpoRiskR")
```
---
## Citation
If you use ExpoRiskR in your research, please cite:
> Chaudhary PP et al. *ExpoRiskR: Exposure‑aware multi‑omics risk modeling framework.*
---
## Support
For questions, issues, or feature requests:
- Bioconductor Support Site: https://support.bioconductor.org
- GitHub Issues: https://github.com/ppchaudhary/ExpoRiskR/issues
