# DirichletMultinomial Dirichlet-multinomial mixture models can be used to describe variability in microbial metagenomic data. This package is an interface to code originally made available by Holmes, Harris, and Quince, 2012, PLoS ONE 7(2): 1-15, as discussed further in the man page for this package, ?DirichletMultinomial. ## Installation Install [DirichletMultinomial][] from [Bioconductor][] with: ```{r} if (!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("DirichletMultinomial") ``` Linux and MacOS with source-level installations require the 'gsl' system dependency. On Debian or Ubuntu ``` sudo apt-get install -y libgsl-dev ``` On Fedora, CentOS or RHEL ``` sudo yum install libgsl-devel ``` On macOS (source installations are not common on macOS, so this step may is not usually necessary) ``` brew install gsl ``` ## Use See the [DirichletMultinomial][] landing page and [vignette][] for use. [DirichletMultinomial]: https://bioconductor.org/packages/DirichletMultinomial [Bioconductor]: https://bioconductor.org [vignette]: https://bioconductor.org/packages/release/bioc/vignettes/DirichletMultinomial/inst/doc/DirichletMultinomial.pdf