Bioconductor Code: DOSE

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NEWS	100644	17 kb
NEWS.md	100644	6 kb
README.Rmd	100644	2 kb
README.md	100644	2 kb

README.md

# DOSE: Disease Ontology Semantic and Enrichment analysis [![](https://img.shields.io/badge/release%20version-3.30.2-green.svg)](https://www.bioconductor.org/packages/DOSE) [![](https://img.shields.io/badge/devel%20version-3.31.3-green.svg)](https://github.com/guangchuangyu/DOSE) [![Bioc](http://www.bioconductor.org/shields/years-in-bioc/DOSE.svg)](https://www.bioconductor.org/packages/devel/bioc/html/DOSE.html#since) [![codecov](https://codecov.io/gh/GuangchuangYu/DOSE/branch/master/graph/badge.svg)](https://codecov.io/gh/GuangchuangYu/DOSE/) [![Project Status: Active - The project has reached a stable, usable state and is being actively developed.](http://www.repostatus.org/badges/latest/active.svg)](http://www.repostatus.org/#active) [![platform](http://www.bioconductor.org/shields/availability/devel/DOSE.svg)](https://www.bioconductor.org/packages/devel/bioc/html/DOSE.html#archives) [![Build Status](http://www.bioconductor.org/shields/build/devel/bioc/DOSE.svg)](https://bioconductor.org/checkResults/devel/bioc-LATEST/DOSE/) [![](https://img.shields.io/badge/download-836274/total-blue.svg)](https://bioconductor.org/packages/stats/bioc/DOSE) [![](https://img.shields.io/badge/download-20017/month-blue.svg)](https://bioconductor.org/packages/stats/bioc/DOSE) This package implements five methods proposed by Resnik, Schlicker, Jiang, Lin and Wang respectively for measuring semantic similarities among DO terms and gene products. Enrichment analyses including hypergeometric model and gene set enrichment analysis are also implemented for discovering disease associations of high-throughput biological data. ## :writing_hand: Authors Guangchuang YU <https://yulab-smu.top> School of Basic Medical Sciences, Southern Medical University Learn more at <https://yulab-smu.top/contribution-knowledge-mining/>. Please cite the following article when using `DOSE`: Guangchuang Yu, Li-Gen Wang, Guang-Rong Yan, Qing-Yu He. DOSE: an R/Bioconductor package for Disease Ontology Semantic and Enrichment analysis. Bioinformatics. 2015, 31(4):608-609.