\name{subpathwayTypes} \alias{subpathwayTypes} \title{All subpathway types} \usage{ subpathwayTypes(grouping) } \arguments{ \item{grouping}{By supplying one of the availiable groupings, specific subsets of availiable subpathway types can be extracted.} } \value{ A vector of all 124 basic subpathway types. See Details section for handly groupings. } \description{ All subpathway types. } \details{ Apart from the 124 distinct subpathway types, several groupings are availiable: \describe{ \item{'all'}{ All subpathway options. } \item{'all.bwd'}{ Forward propagation. } \item{'all.fwd'}{Backward propagation. } \item{'all.stream'}{All possible genes targeting or are targeted via a path starting from a gene of interest.} \item{'all.neighbourhood'}{All adjacent genes of a gene of interest with incoming or outgoing links.} \item{'all.cascade'}{A finite sequence of interactions connecting a sequence of genes starting or ending from a gene of interest.} \item{'all.community'}{Group of genes sharing common properties.} \item{'all.component'}{Subgraphs on which any two vertices are (strongly) connected to each other by paths.} \item{ }{} \item{'all.functional'}{Forward and backward streams starting from genes/nodes with crucial functional role within the network. Individual options include GO_bp, GO_cc, GO_mf, KEGG, Disease_OMIM, Disease_GAD, Drug_DrugBank, miRNA, TF, DEG, which are defined below.} \item{'all.GO_bp'}{Genes acting as a bridge among Gene Ontology (GO) Biological Process terms. } \item{'all.GO_cc'}{Genes acting as a bridge among Gene Ontology (GO) Cellular Component terms. } \item{'all.GO_mf'}{Genes acting as a bridge among Gene Ontology (GO) Molecular Function terms. } \item{'all.KEGG'}{Genes acting as a bridge among KEGG pathway maps. } \item{'all.Disease_OMIM'}{Genes acting as a bridge among OMIM Disease targets.} \item{'all.Disease_GAD'}{Genes acting as a bridge among GAD Disease targets.} \item{'all.Drug_DrugBank'}{Genes acting as a bridge among DrugBank Drug targets.} \item{'all.miRNA'}{Genes acting as a bridge among microRNA-gene targets. } \item{'all.TF'}{Genes acting as a bridge among TF-gene targets. } \item{'all.DEG'}{Genes with highly Differentially expressed by each experimental data. } \item{}{} \item{'all.topological'}{Forward and backward streams starting from genes/nodes with crucial topological role within the network. Individual options include degree, betweenness, closeness, hub_score, eccentricity, page_rank, start_nodes which are defined below.} \item{'all.degree'}{Number of gene's adjacent interactions.} \item{'all.betweenness'}{Number of shortest paths from all vertices to others passing through a node.} \item{'all.closeness'}{Inverse of farness, which is the sum of distances to all other nodes.} \item{'all.hub_score'}{Kleinberg's hub centrality score.} \item{'all.eccentricity'}{Shortest path distance from the farthest other node in the graph.} \item{'all.page_rank'}{Google Page Rank.} \item{'all.start_nodes'}{Gene nodes without incoming links.} \item{}{} } An exhaustive list of all 124 subpathway types follows: \tabular{ll}{ \tab \cr STREAM-TOPOLOGICAL \tab \cr 'bwd.stream.topological.degree' \tab 'fwd.stream.topological.degree' \cr 'bwd.stream.topological.betweenness' \tab 'fwd.stream.topological.betweenness' \cr 'bwd.stream.topological.closeness' \tab 'fwd.stream.topological.closeness' \cr 'bwd.stream.topological.hub_score' \tab 'fwd.stream.topological.hub_score' \cr 'bwd.stream.topological.eccentricity' \tab 'fwd.stream.topological.eccentricity' \cr 'bwd.stream.topological.page_rank' \tab 'fwd.stream.topological.page_rank' \cr 'bwd.stream.topological.start_nodes' \tab 'fwd.stream.topological.start_nodes' \cr \tab \cr STREAM-FUNCTIONAL \tab \cr 'bwd.stream.functional.GO_bp' \tab 'fwd.stream.functional.GO_bp' \cr 'bwd.stream.functional.GO_cc' \tab 'fwd.stream.functional.GO_cc' \cr 'bwd.stream.functional.GO_mf' \tab 'fwd.stream.functional.GO_mf' \cr 'bwd.stream.functional.KEGG' \tab 'fwd.stream.functional.KEGG' \cr 'bwd.stream.functional.Disease_OMIM' \tab 'fwd.stream.functional.Disease_OMIM' \cr 'bwd.stream.functional.Disease_GAD' \tab 'fwd.stream.functional.Disease_GAD' \cr 'bwd.stream.functional.Drug_DrugBank' \tab 'fwd.stream.functional.Drug_DrugBank' \cr 'bwd.stream.functional.miRNA' \tab 'fwd.stream.functional.miRNA' \cr 'bwd.stream.functional.TF' \tab 'fwd.stream.functional.TF' \cr 'bwd.stream.functional.DEG' \tab 'fwd.stream.functional.DEG' \cr \tab \cr NEIGHBOURHOOD-TOPOLOGICAL \tab \cr 'bwd.neighbourhood.topological.degree' \tab 'fwd.neighbourhood.topological.degree' \cr 'bwd.neighbourhood.topological.betweenness' \tab 'fwd.neighbourhood.topological.betweenness' \cr 'bwd.neighbourhood.topological.closeness' \tab 'fwd.neighbourhood.topological.closeness' \cr 'bwd.neighbourhood.topological.hub_score' \tab 'fwd.neighbourhood.topological.hub_score' \cr 'bwd.neighbourhood.topological.eccentricity' \tab 'fwd.neighbourhood.topological.eccentricity' \cr 'bwd.neighbourhood.topological.page_rank' \tab 'fwd.neighbourhood.topological.page_rank' \cr 'bwd.neighbourhood.topological.start_nodes' \tab 'fwd.neighbourhood.topological.start_nodes' \cr \tab \cr NEIGHBOURHOOD-FUNCTIONAL \tab \cr 'bwd.neighbourhood.functional.GO_bp' \tab 'fwd.neighbourhood.functional.GO_bp' \cr 'bwd.neighbourhood.functional.GO_cc' \tab 'fwd.neighbourhood.functional.GO_cc' \cr 'bwd.neighbourhood.functional.GO_mf' \tab 'fwd.neighbourhood.functional.GO_mf' \cr 'bwd.neighbourhood.functional.KEGG' \tab 'fwd.neighbourhood.functional.KEGG' \cr 'bwd.neighbourhood.functional.Disease_OMIM' \tab 'fwd.neighbourhood.functional.Disease_OMIM' \cr 'bwd.neighbourhood.functional.Disease_GAD' \tab 'fwd.neighbourhood.functional.Disease_GAD' \cr 'bwd.neighbourhood.functional.Drug_DrugBank' \tab 'fwd.neighbourhood.functional.Drug_DrugBank' \cr 'bwd.neighbourhood.functional.miRNA' \tab 'fwd.neighbourhood.functional.miRNA' \cr 'bwd.neighbourhood.functional.TF' \tab 'fwd.neighbourhood.functional.DEG' \cr \tab \cr CASCADE-TOPOLOGICAL \tab \cr 'bwd.cascade.topological.degree' \tab 'fwd.cascade.topological.degree' \cr 'bwd.cascade.topological.betweenness' \tab 'fwd.cascade.topological.betweenness' \cr 'bwd.cascade.topological.closeness' \tab 'fwd.cascade.topological.closeness' \cr 'bwd.cascade.topological.hub_score' \tab 'fwd.cascade.topological.hub_score' \cr 'bwd.cascade.topological.eccentricity' \tab 'fwd.cascade.topological.eccentricity' \cr 'bwd.cascade.topological.page_rank' \tab 'fwd.cascade.topological.page_rank' \cr 'bwd.cascade.topological.start_nodes' \tab 'fwd.cascade.topological.start_nodes' \cr \tab \cr \tab \cr CASCADE-FUNCTIONAL \tab \cr 'bwd.cascade.functional.GO_bp' \tab 'fwd.cascade.functional.GO_bp' \cr 'bwd.cascade.functional.GO_cc' \tab 'fwd.cascade.functional.GO_cc' \cr 'bwd.cascade.functional.GO_mf' \tab 'fwd.cascade.functional.GO_mf' \cr 'bwd.cascade.functional.KEGG' \tab 'fwd.cascade.functional.KEGG' \cr 'bwd.cascade.functional.Disease_OMIM' \tab 'fwd.cascade.functional.Disease_OMIM' \cr 'bwd.cascade.functional.Disease_GAD' \tab 'fwd.cascade.functional.Disease_GAD' \cr 'bwd.cascade.functional.Drug_DrugBank' \tab 'fwd.cascade.functional.Drug_DrugBank' \cr 'bwd.cascade.functional.miRNA' \tab 'fwd.cascade.functional.miRNA' \cr 'bwd.cascade.functional.TF' \tab 'fwd.cascade.functional.TF' \cr 'bwd.cascade.functional.DEG' \tab 'fwd.cascade.functional.DEG' \cr \tab \cr COMMUNITY \tab \cr 'community.walktrap' \tab 'community.edge_betweenness' \cr 'community.fast_greedy' \tab 'community.leading_eigen' \cr 'community.infomap' \tab 'community.louvain' \cr \tab \cr COMPONENT-CLIQUES \tab \cr 'component.max_cliques' \tab 'component.decompose' \cr 'component.3-cliques' \tab ... \cr ... \tab 'component.9-cliques' \cr \tab \cr COMPONENT-CORENESS \tab \cr 'component.3-coreness' \tab ... \cr ... \tab 'component.9-coreness' \cr } } \examples{ basic.types <- subpathwayTypes() stream.types <- subpathwayTypes(grouping='all.stream') }