Package: ChIPanalyser Type: Package Title: ChIPanalyser: Predicting Transcription Factor Binding Sites Authors@R: c( person(c("Patrick", "CN"), "Martin", role=c("cre", "aut"), email="pcnmartin@gmail.com"), person(c("Nicolea","Radu"), "Zabet", role="aut")) Version: 1.29.0 Date: 2017-09-01 Author: Patrick C.N.Martin & Nicolae Radu Zabet Maintainer: Patrick C.N. Martin <pcnmartin@gmail.com> Citation: Zabet NR, Adryan B (2015) Estimating binding properties of transcription factors from genome-wide binding profiles. Nucleic Acids Res., 43, 84–94. Description: ChIPanalyser is a package to predict and understand TF binding by utilizing a statistical thermodynamic model. The model incorporates 4 main factors thought to drive TF binding: Chromatin State, Binding energy, Number of bound molecules and a scaling factor modulating TF binding affinity. Taken together, ChIPanalyser produces ChIP-like profiles that closely mimic the patterns seens in real ChIP-seq data. License: GPL-3 Collate: 2AllS4Class_ProfileParameters.R 3AllGenerics.R 4AllMethods.R AllInitialize.R AllShowMethods.R computeChIPProfile.R computeOccupancy.R computeOptimal.R computePWMScore.R computeGenomeWide.R parallelInternalFunctionsDev.R GenomicProfileGenericFunctions.R plotOccupancy.R plotOptimalHeatMapDev.R DataPreprocessingDev.R DataPreprocessingGenericFunctionsDev.R profileAccuracyEstimateDev.R GAAnalysis.R GAGeneric.R Depends: R (>= 3.5.0),GenomicRanges, Biostrings, BSgenome, RcppRoll, parallel Imports: methods, IRanges, S4Vectors,grDevices,graphics,stats,utils,rtracklayer,ROCR, BiocManager,GenomeInfoDb,RColorBrewer Suggests: BSgenome.Dmelanogaster.UCSC.dm6,knitr, RUnit, BiocGenerics Encoding: UTF-8 LazyData: true biocViews: Software, BiologicalQuestion, WorkflowStep, Transcription, Sequencing, ChipOnChip, Coverage, Alignment, ChIPSeq, SequenceMatching, DataImport ,PeakDetection VignetteBuilder: knitr RoxygenNote: 7.2.1