Type: Package Package: CellaRepertorium Title: Data structures, clustering and testing for single cell immune receptor repertoires (scRNAseq RepSeq/AIRR-seq) Version: 0.4.0 Authors@R: c(person(given = "Andrew", family = "McDavid", role = c('aut', 'cre'), email = "Andrew_McDavid@urmc.rochester.edu"), person(given = "Yu", family = "Gu", role = "aut", email = "Yu_Gu@urmc.rochester.edu"), person(given = 'Thomas Lin', family = 'Pedersen', role = 'ctb')) Description: Methods to cluster and analyze high-throughput single cell immune cell repertoires, especially from the 10X Genomics VDJ solution. Contains an R interface to CD-HIT (Li and Godzik 2006). Methods to visualize and analyze paired heavy-light chain data. Tests for specific expansion, as well as omnibus oligoclonality under hypergeometric models. License: GPL-3 Depends: R (>= 3.5.0) Imports: dplyr, tibble, stringr, Biostrings, Rcpp, reshape2, methods, rlang, purrr, Matrix, S4Vectors, tidyr, forcats, progress, stats, utils Suggests: testthat, readr, knitr, rmarkdown, ggplot2, BiocStyle, ggdendro, broom, lme4, RColorBrewer, SingleCellExperiment, scater LinkingTo: Rcpp VignetteBuilder: knitr Encoding: UTF-8 LazyData: true NeedsCompilation: yes RoxygenNote: 6.1.1 URL: https://github.com/amcdavid/CellaRepertorium BugReports: https://github.com/amcdavid/CellaRepertorium/issues Roxygen: list(markdown = TRUE) biocViews: RNASeq, Transcriptomics, SingleCell, TargetedResequencing, Technology, ImmunoOncology, Clustering