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<p align="center">
<img src="man/figures/CNVMetrics_text.jpg" alt="CNVMetrics"> <img src="man/figures/CNVMetrics.png" align="right" alt="" width="120" />
</p>
The **_CNVMetrics_** package offers multiple quantitative metrics of similarity between copy number profiles.
Among these are metrics based on CNV status calls only (amplification/deletion status) or on the level of amplification/deletion. In addition, a visualization tool is provided to explore resulting metrics.
## Citing ##
If you use this package for a publication, we would ask you to cite the following:
>Belleau P, DeschĂȘnes A, Beyaz S et al. CNVMetrics package: Quantifying similarity between copy number profiles [version 1; not peer reviewed]. F1000Research 2021, 10:737 (slides) (doi: 10.7490/f1000research.1118704.1)
[F1000Research poster](http://www.doi.org/10.7490/f1000research.1118704.1)
## Authors ##
[Astrid Deschênes](http://ca.linkedin.com/in/astriddeschenes "Astrid Deschênes"),
[Pascal Belleau](http://ca.linkedin.com/in/pascalbelleau "Pascal Belleau"),
[David A. Tuveson](http://tuvesonlab.labsites.cshl.edu/ "David A. Tuveson") and
[Alexander Krasnitz](https://www.cshl.edu/research/faculty-staff/alexander-krasnitz/ "Alexander Krasnitz")
## Bioconductor Package ##
[![Bioconductor Time](https://bioconductor.org/shields/years-in-bioc/CNVMetrics.svg)](https://bioconductor.org/packages/CNVMetrics)
The **_CNVMetrics_** package is now an official package of [Bioconductor](http://bioconductor.org/).
The current release can be directly downloaded from their website:
[Current release](https://bioconductor.org/packages/CNVMetrics)
However, all official releases can be downloaded from this site:
[All releases](https://github.com/KrasnitzLab/CNVMetrics/releases)
## Documentation ##
[CNVMetrics Website](https://krasnitzlab.github.io/CNVMetrics/)
[CNVMetrics Get Started](https://krasnitzlab.github.io/CNVMetrics/articles/CNVMetrics.html)
## Installation ##
To install this package from [Bioconductor](https://bioconductor.org/packages/CNVMetrics), start R (version "4.2") and enter:
if (!requireNamespace("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("CNVMetrics")
To install the latest version accessible using the [devtools](https://cran.r-project.org/web/packages/devtools/index.html)
package:
## Load required package
library(devtools)
## Install the latest version of CNVMetrics
devtools::install_github('KrasnitzLab/CNVMetrics')
## License ##
This package and the underlying **_CNVMetrics_** code are distributed under
the Artistic license 2.0. You are free to use and redistribute this software.
For more information on Artistic 2.0 License see
[http://opensource.org/licenses/Artistic-2.0](http://opensource.org/licenses/Artistic-2.0)
## Bugs/Feature requests ##
[Please contact us](https://github.com/KrasnitzLab/CNVMetrics/issues) for bug fixes or with feature requests.
Thanks!