Name Mode Size
R 040000
inst 040000
man 040000
tests 040000
vignettes 040000
.gitignore 100644 0 kb
DESCRIPTION 100644 2 kb
NAMESPACE 100644 4 kb
NEWS.md 100644 10 kb
README.md 100644 1 kb
README.md
# ATACseqQC [![platforms](http://bioconductor.org/shields/availability/devel/ATACseqQC.svg)](http://bioconductor.org/packages/devel/bioc/html/ATACseqQC.html) [![build](http://bioconductor.org/shields/build/devel/bioc/ATACseqQC.svg)](http://bioconductor.org/packages/devel/bioc/html/ATACseqQC.html) ATAC sequencing Quality Control ATAC-seq, an assay for Transposase-Accessible Chromatin using sequencing, is a rapid and sensitive method for chromatin accessibility analysis. It was developed as an alternative method to MNase-seq, FAIRE-seq and DNAse-seq. Comparing to the other methods, ATAC-seq requires less amount of the biological samples and time to process. In the process of analyzing several ATAC-seq dataset produced in our labs, we learned some of the unique aspects of the quality assessment for ATAC-seq data.To help users to quickly assess whether their ATAC-seq experiment is successful, we developed ATACseqQC package partially following the guideline published in Nature Method 2013 (Greenleaf et al.), including diagnostic plot of fragment size distribution, proportion of mitochondria reads, nucleosome positioning pattern, and CTCF or other Transcript Factor footprints. ## Installation To install this package, start R and enter: ```r library(BiocManager) BiocManager::install("ATACseqQC") ``` ## Documentation To view documentation of ATACseqQC, start R and enter: ```r browseVignettes("ATACseqQC") ```