Name Mode Size
R 040000
data 040000
docs 040000
man 040000
tests 040000
vignettes 040000
.travis.yml 100644 1 kb
DESCRIPTION 100644 2 kb
LICENSE 100644 1 kb
NAMESPACE 100644 0 kb
NEWS 100644 0 kb 100644 1 kb
_pkgdown.yml 100644 1 kb
[![Build Status](]( # ASSIGN: Adaptive Signature Selection and InteGratioN __Author__: Ying Shen, Andrea H. Bild, David Jenkins, and W. Evan Johnson __Maintainer__: [David Jenkins](, [W. Evan Johnson](, [Mumtehena Rahman](, and Ying Shen <> ASSIGN is a computational tool to evaluate the pathway deregulation/activation status in individual patient samples. ASSIGN employs a flexible Bayesian factor analysis approach that adapts predetermined pathway signatures derived either from knowledge-based literature or from perturbation experiments to the cell-/tissue-specific pathway signatures. The deregulation/activation level of each context-specific pathway is quantified to a score, which represents the extent to which a patient sample encompasses the pathway deregulation/activation signature. ## Installation ASSIGN is available on Bioconductor: ```r if (!requireNamespace("BiocManager", quietly=TRUE)) install.packages("BiocManager") BiocManager::install("ASSIGN") ``` Or install the development version from github: ```r # install.packages("devtools") devtools::install_github("compbiomed/ASSIGN") ```